The first record of Mass celebrated in Market Drayton occurred in 1856 when Father James Kenny of Whitchurch celebrated Mass in a private house. After this date, there are records of priests from Swynnerton Hall occassionally celebrating Mass here, then from 1864 Market Drayton was served from Crewe and then from Nantwich until 1884 when Father Laurence Levett came as the first resident priest.
| • Father Laurence Levett | 1884-1890 |
| • Father David Williams | 1890-1894 |
| • Father Henry Lynch | 1894-1902 |
| • Canon Charles Langdon | 1902-1907 |
| • Father Norbert Kelly | 1907-1913 |
| • Father Thomas Mulcahy | 1913-1924 |
| • Father Henry Rope | 1924-1926 |
| • Father Aloysius Wilson | 1926-1931 |
| • Father John Donnelly | 1931-1933 |
| • Father Gerald Cavanagh | 1933-1963 |
| • Father John Marmion | 1963-1970 |
| • Father Colin Doyle | 1970-1983 |
| • Father David Craig | 1983-1984 |
| • Father David Woodier | 1984-1990 |
| • Father Patrick Shivnan | 1990-1999 |
| • Father John McLeish | 1999-2010 |
| • Father Kevin Prince | 2010-2012 |
| • Father Lucas Ngwa | 2012-2014 |
| • Father Anthony Wild | 2014-2022 |
| • Father Lee Bennett | 2022- |